Jump to content

Iclazepam

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Boghog (talk | contribs) at 17:07, 3 September 2020 (templated cites). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Iclazepam
Identifiers
  • 7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H-1,4-benzodiazepin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H21ClN2O2
Molar mass368.86 g·mol−1
3D model (JSmol)
  • ClC1=CC2=C(C=C1)N(CCOCC3CC3)C(CN=C2C4=CC=CC=C4)=O
  • InChI=1S/C21H21ClN2O2/c22-17-8-9-19-18(12-17)21(16-4-2-1-3-5-16)23-13-20(25)24(19)10-11-26-14-15-6-7-15/h1-5,8-9,12,15H,6-7,10-11,13-14H2 checkY
  • Key:PLRHQQPBNXIHAZ-UHFFFAOYSA-N checkY
  (verify)

Iclazepam (Clazepam) is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and is around the same potency as chlordiazepoxide.

Iclazepam is a derivative of nordazepam substituted with a cyclopropylmethoxyethyl group on the N1 nitrogen. Once in the body, iclazepam is quickly metabolised to nordazepam and its N-(2-hydroxyethyl) derivative, which are thought to be mainly responsible for its effects.[1]

See also

References

  1. ^ Giudicelli JF, Berdeaux A, Idrissi N, Richer C (January 1978). "Clazepam: pharmacokinetics and effects on performance". British Journal of Clinical Pharmacology. 5 (1): 65–9. doi:10.1111/j.1365-2125.1978.tb01599.x. PMC 1429233. PMID 23135.
Stub icon

This sedative-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Iclazepam&oldid=976561027"