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SLC46A1

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Template:PBB Solute carrier family 46 (folate transporter), member 1 (SLC46A1) also known as proton-coupled folate transporter (PCFT), is a protein which in humans is encoded by the SLC46A1 gene.[1][2][3]

Function

SLC46A1 is responsible for the intestinal uptake of folate.[4]

References

  1. ^ "Entrez Gene: PCFT proton-coupled folate transporter".
  2. ^ Shayeghi M, Latunde-Dada GO, Oakhill JS, Laftah AH, Takeuchi K, Halliday N, Khan Y, Warley A, McCann FE, Hider RC, Frazer DM, Anderson GJ, Vulpe CD, Simpson RJ, McKie AT (September 2005). "Identification of an intestinal heme transporter". Cell. 122 (5): 789–801. doi:10.1016/j.cell.2005.06.025. PMID 16143108.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Sharma S, Dimasi D, Bröer S, Kumar R, Della NG (April 2007). "Heme carrier protein 1 (HCP1) expression and functional analysis in the retina and retinal pigment epithelium". Exp. Cell Res. 313 (6): 1251–9. doi:10.1016/j.yexcr.2007.01.019. PMID 17335806.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ Nakai Y, Inoue K, Abe N, Hatakeyama M, Ohta KY, Otagiri M, Hayashi Y, Yuasa H (August 2007). "Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter". J. Pharmacol. Exp. Ther. 322 (2): 469–76. doi:10.1124/jpet.107.122606. PMID 17475902.{{cite journal}}: CS1 maint: multiple names: authors list (link)

Further reading

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