SLC23A1

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SLC23A1
Identifiers
Aliases SLC23A1, SLC23A2, SVCT1, YSPL3, solute carrier family 23 member 1
External IDs MGI: 1341903 HomoloGene: 40769 GeneCards: 9963
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005847
NM_152685

NM_011397

RefSeq (protein)

NP_005838.3
NP_689898.2

NP_035527.3

Location (UCSC) Chr 5: 139.37 – 139.38 Mb Chr 18: 35.61 – 35.63 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Solute carrier family 23 member 1 is a protein that in humans is encoded by the SLC23A1 gene.[3][4][5]

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Faaland CA; Race JE; Ricken G; Warner FJ; Williams WJ; Holtzman EJ (Dec 1998). "Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters". Biochim Biophys Acta. 1442 (2–3): 353–60. doi:10.1016/S0167-4781(98)00151-1. PMID 9804989. 
  4. ^ Tsukaguchi H; Tokui T; Mackenzie B; Berger UV; Chen XZ; Wang Y; Brubaker RF; Hediger MA (Jun 1999). "A family of mammalian Na+-dependent L-ascorbic acid transporters". Nature. 399 (6731): 70–5. doi:10.1038/19986. PMID 10331392. 
  5. ^ a b "Entrez Gene: SLC23A1 solute carrier family 23 (nucleobase transporters), member 1". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.