SLC30A3

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SLC30A3
Identifiers
Aliases SLC30A3, ZNT3, solute carrier family 30 member 3
External IDs MGI: 1345280 HomoloGene: 74470 GeneCards: 7781
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003459
NM_001318949
NM_001318950
NM_001318951

NM_011773

RefSeq (protein)

NP_003450.2
NP_001305878.1
NP_001305879.1
NP_001305880.1

NP_035903.2

Location (UCSC) Chr 2: 27.25 – 27.28 Mb Chr 5: 31.09 – 31.11 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Zinc transporter 3 also known as solute carrier family 30 member 3 is a protein in humans that is encoded by the SLC30A3 gene.[3]

The SLC30A3 gene codes for the ZnT-3 SLC30A family membrane transport protein. ZnT-3 is required for the accumulation of zinc ions inside synaptic vesicles.[4] In mice, ZnT-3 is required for some forms of memory that depend on the hippocampus and the amygdala.[5] Zinc transport by ZnT-3 modulates memory formation by acting through the extracellular signal-regulated kinases signaling pathway.[6] Angiotensin II-induced senescence of vascular smooth muscle cells requires down-regulation of ZnT-3 and ZnT-10.[7]

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