Long-chain fatty acid transport protein 1

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SLC27A1
Identifiers
AliasesSLC27A1, ACSVL5, FATP, FATP1, FATP-1, solute carrier family 27 member 1
External IDsMGI: 1347098 HomoloGene: 8063 GeneCards: SLC27A1
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for SLC27A1
Genomic location for SLC27A1
Band19p13.11Start17,468,769 bp[1]
End17,506,168 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_198580

NM_011977
NM_001357180
NM_001357181
NM_001357182

RefSeq (protein)

NP_940982

NP_036107
NP_001344109
NP_001344110
NP_001344111

Location (UCSC)Chr 19: 17.47 – 17.51 MbChr 8: 71.57 – 71.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Long-chain fatty acid transport protein 1 is a protein that in humans is encoded by the SLC27A1 gene.[5][6]

Structure[edit]

The SLC27A1 gene is located on the 19th chromosome, with its specific location being 19p13.11. The gene contains 15 exons.[6] SLC27A1 encodes a 71.1 kDa protein that is composed of 646 amino acids; 26 peptides have been observed through mass spectrometry data.[7][8]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130304 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031808 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Martin G, Nemoto M, Gelman L, Geffroy S, Najib J, Fruchart JC, Roevens P, de Martinville B, Deeb S, Auwerx J (June 2000). "The human fatty acid transport protein-1 (SLC27A1; FATP-1) cDNA and gene: organization, chromosomal localization, and expression". Genomics. 66 (3): 296–304. doi:10.1006/geno.2000.6191. PMID 10873384.
  6. ^ a b "Entrez Gene: SLC27A1 solute carrier family 27 (fatty acid transporter), member 1".
  7. ^ ]Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, Zelaya I, Liem D, Meyer D, Odeberg J, Fang C, Lu HJ, Xu T, Weiss J, Duan H, Uhlen M, Yates JR, Apweiler R, Ge J, Hermjakob H, Ping P (October 2013). "Integration of cardiac proteome biology and medicine by a specialized knowledgebase". Circulation Research. 113 (9): 1043–53. doi:10.1161/CIRCRESAHA.113.301151. PMC 4076475. PMID 23965338.
  8. ^ "Long-chain fatty acid transport protein 1". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB).

Further reading[edit]

  • Meirhaeghe A, Cottel D, Amouyel P, Dallongeville J (2006). "Lack of association between certain candidate gene polymorphisms and the metabolic syndrome". Molecular Genetics and Metabolism. 86 (1–2): 293–9. doi:10.1016/j.ymgme.2005.05.006. PMID 15978856.
  • García-Martínez C, Marotta M, Moore-Carrasco R, Guitart M, Camps M, Busquets S, Montell E, Gómez-Foix AM (June 2005). "Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells". American Journal of Physiology. Cell Physiology. 288 (6): C1264–72. doi:10.1152/ajpcell.00271.2004. PMID 15897321.
  • Gertow K, Skoglund-Andersson C, Eriksson P, Boquist S, Orth-Gomér K, Schenck-Gustafsson K, Hamsten A, Fisher RM (April 2003). "A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution". Atherosclerosis. 167 (2): 265–73. doi:10.1016/S0021-9150(02)00454-9. PMID 12818409.
  • Hatch GM, Smith AJ, Xu FY, Hall AM, Bernlohr DA (September 2002). "FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells". Journal of Lipid Research. 43 (9): 1380–9. doi:10.1194/jlr.M200130-JLR200. PMID 12235169.
  • Hirsch D, Stahl A, Lodish HF (July 1998). "A family of fatty acid transporters conserved from mycobacterium to man". Proceedings of the National Academy of Sciences of the United States of America. 95 (15): 8625–9. doi:10.1073/pnas.95.15.8625. PMC 21126. PMID 9671728.
  • Schaffer JE, Lodish HF (November 1994). "Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein". Cell. 79 (3): 427–36. doi:10.1016/0092-8674(94)90252-6. PMID 7954810.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.