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HOT-17, or 2,5-dimethoxy-4-(β-isobutylthio)-N-hydroxyphenethylamine, is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book, PiHKAL (Phenethylamines i Have Known And Loved).
HOT-17's full chemical name is 2-[4-(2-isobutylthio)-2,5-dimethoxyphenyl-N-hydroxyethanamine. It has structural properties similar to 2C-T-17 and to other drugs in the HOT- series, with the most closely related compounds being HOT-2 and HOT-7.
The dosage range of HOT-17 is typically 70-120mg and its duration is approximately 12–18 hours according to Shulgin. HOT-17 produces time distortion and general psychedelia. It also has little to no body load.
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