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Interleukin 22 receptor, alpha 1
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols IL22RA1 ; CRF2-9; IL22R; IL22R1
External IDs OMIM605457 HomoloGene10943 IUPHAR: 1731 GeneCards: IL22RA1 Gene
Species Human Mouse
Entrez 58985 230828
Ensembl ENSG00000142677 ENSMUSG00000037157
UniProt Q8N6P7 Q80XZ4
RefSeq (mRNA) NM_021258 NM_178257
RefSeq (protein) NP_067081 NP_839988
Location (UCSC) Chr 1:
24.45 – 24.47 Mb
Chr 4:
135.73 – 135.75 Mb
PubMed search [1] [2]

Interleukin 22 receptor, alpha 1 is a protein that in humans is encoded by the IL22RA1 gene.[1]


The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10RB/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36.


Further Reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.