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Segesterone acetate/ethinylestradiol

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Ethinylestradiol /
segesterone acetate
Combination of
EthinylestradiolEstrogen
Segesterone acetateProgestogen
Clinical data
Trade namesAnnovera
Other namesEE/SGA; EE/SA
Routes of
administration
Vaginal ring
Identifiers
KEGG

Ethinylestradiol/segesterone acetate (EE/SGA), sold under the brand name Annovera, is a contraceptive vaginal ring and combined form of hormonal birth control which contains ethinylestradiol, an estrogen, and segesterone acetate, a progestin.[1] It contains 17.4 mg ethinylestradiol and 103 mg segesterone acetate, releases an average of 13 μg ethinylestradiol and 0.15 mg segesterone acetate per day.[1][2]

Annovera is inserted into the vagina and left for 21 days, then removed, washed and stored for 7 days, during which the user experiences a period (withdrawal bleeding.) This can be repeated 13 times, for one full year of use.[3] Unlike NuvaRing, another vaginal ring contraceptive, Annovera does not need to be refrigerated before being dispensed to a patient and can be stored at temperatures up to 30 degrees Celsius.[4]

The medication was developed by the Population Council, an international non-profit organization, and licensed to TherapeuticsMD. It was approved for use in the United States on 10 August 2018.[2]

See also

References

  1. ^ a b https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/209627s000lbl.pdf
  2. ^ a b https://ir.therapeuticsmd.com/news-releases/news-release-details/therapeuticsmd-announces-fda-approval-annoveratm-segesterone
  3. ^ "FDA approves new vaginal ring for one year of birth control".
  4. ^ "FDA prescribing information for Annovera" (PDF).