Mestranol/norethisterone

Mestranol/norethisterone
Combination of
Mestranol	Estrogen
Norethisterone	Progestogen
Clinical data
Trade names	Norethin, Noriday, Norinyl, Norquen, Ortho-Novum, others
AHFS/Drugs.com	Monograph
Routes of; administration	By mouth
Legal status
Legal status	US: ℞-only;

Mestranol/norethisterone (brand names Norethin, Noriday, Norinyl, Norquen, Ortho-Novum, others) is a combination of the estrogen ethinylestradiol and the progestin norethisterone (norethindrone) which was introduced in 1963 and was the second combined oral contraceptive to be marketed, following mestranol/noretynodrel in 1960.^[1] Although most mestranol-containing oral contraceptive formulations have been discontinued, the combination remains available today in the United States in a single formulation under the brand name Norinyl 1+50 28-Day.^[2] It has largely been superseded by ethinylestradiol/norethisterone, which has been marketed under many of the same brand names.^[3]^[4]

References

^ Marks L (2010). Sexual Chemistry: A History of the Contraceptive Pill. Yale University Press. pp. 74, 76. ISBN 978-0-300-16791-7.
^ "Drugs@FDA: FDA Approved Drug Products". United States Food and Drug Administration. Retrieved 22 December 2016.
^ Blum RW (22 October 2013). Adolescent Health Care: Clinical Issues. Elsevier Science. pp. 216–. ISBN 978-1-4832-7738-7.
^ Varney H, Kriebs JM, Gegor CL (2004). Varney's Midwifery. Jones & Bartlett Learning. pp. 515–. ISBN 978-0-7637-1856-5.

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[Marks2010-1] Marks L (2010). Sexual Chemistry: A History of the Contraceptive Pill. Yale University Press. pp. 74, 76. ISBN 978-0-300-16791-7.

[Drugs@FDA-2] "Drugs@FDA: FDA Approved Drug Products". United States Food and Drug Administration. Retrieved 22 December 2016.

[Blum2013-3] Blum RW (22 October 2013). Adolescent Health Care: Clinical Issues. Elsevier Science. pp. 216–. ISBN 978-1-4832-7738-7.

[VarneyKriebs2004-4] Varney H, Kriebs JM, Gegor CL (2004). Varney's Midwifery. Jones & Bartlett Learning. pp. 515–. ISBN 978-0-7637-1856-5.

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See also

References