Faxeladol

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Faxeladol
Clinical data
Other namesFaxeladol
ATC code
  • None
Identifiers
  • 3-[(1R,2R)-2-dimethylaminomethylcyclohexyl]phenol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H23NO
Molar mass233.36 g/mol g·mol−1
3D model (JSmol)
  • Oc1cccc(c1)[C@@H]2CCCC[C@H]2CN(C)C
  • InChI=1S/C15H23NO/c1-16(2)11-13-6-3-4-9-15(13)12-7-5-8-14(17)10-12/h5,7-8,10,13,15,17H,3-4,6,9,11H2,1-2H3/t13-,15-/m0/s1 checkY
  • Key:JIRYWFYYBBRJAN-ZFWWWQNUSA-N checkY
  (verify)

Faxeladol (INN, USAN) (code names GRTA-9906, GRTA-0009906, EM-906, GCR-9905, GRT-TA300) is an opioid analgesic which was developed by Grünenthal GmbH but was never marketed for medical use anywhere in the world. It is related to tramadol and ciramadol, and was developed shortly after tramadol in the late 1970s. Similarly to tramadol, it was believed faxeladol would have analgesic, as well as antidepressant effects, due to its action on serotonin and norepinephrine reuptake. In various studies in the 1970s alongside tramadol, faxeladol was seen to be slightly more potent than tramadol, but with a higher rate of sudden seizures than tramadol, which is known to cause seizures without warning in some users.

See also

References



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