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Proton-coupled amino acid transporter 1

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SLC36A1
Identifiers
AliasesSLC36A1, Dct1, LYAAT1, PAT1, TRAMD3, solute carrier family 36 member 1
External IDsOMIM: 606561; MGI: 2445299; HomoloGene: 121860; GeneCards: SLC36A1; OMA:SLC36A1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001308150
NM_001308151
NM_078483
NM_001349740

NM_153139

RefSeq (protein)

NP_001295079
NP_001295080
NP_510968
NP_001336669

NP_694779

Location (UCSC)Chr 5: 151.44 – 151.49 MbChr 11: 55.1 – 55.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene.[5][6][7]

This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.[7]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000123643Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020261Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Boll M, Foltz M, Rubio-Aliaga I, Kottra G, Daniel H (Jun 2002). "Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters". J Biol Chem. 277 (25): 22966–73. doi:10.1074/jbc.M200374200. PMID 11959859.
  6. ^ Sagne C, Agulhon C, Ravassard P, Darmon M, Hamon M, El Mestikawy S, Gasnier B, Giros B (Jun 2001). "Identification and characterization of a lysosomal transporter for small neutral amino acids". Proc Natl Acad Sci U S A. 98 (13): 7206–11. Bibcode:2001PNAS...98.7206S. doi:10.1073/pnas.121183498. PMC 34647. PMID 11390972.
  7. ^ a b "Entrez Gene: SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.