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RU-28306

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This is an old revision of this page, as edited by DePiep (talk | contribs) at 20:48, 2 April 2016 (Remove redundant parameters InChI, InChIKey (StdInChI, StdInChIKey are used). See Talk (via AWB script)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

RU-28306
Identifiers
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H16N2
Molar mass200.279 g/mol g·mol−1
3D model (JSmol)
  • c13c(C2)cccc1ncc3CC2N(C)C
  • InChI=1S/C13H16N2/c1-15(2)11-6-9-4-3-5-12-13(9)10(7-11)8-14-12/h3-5,8,11,14H,6-7H2,1-2H3
  • Key:BQOANWOQEHVATQ-UHFFFAOYSA-N

RU-28306 is a tricyclic tryptamine derivative which acts as a serotonin receptor agonist, with selectivity for 5-HT1 and 5-HT2 subtypes. It can be regarded either as a conformationally constrained derivative of DMT, or a structurally simplified analogue of LSD, but the binding affinity of racemic RU-28306 is closer to that of DMT, though with relatively higher affinity for 5-HT2 subtypes and lower for 5-HT1.[1]

See also

References

  1. ^ Taylor EW, Nikam S, Weck B, Martin A, Nelson D. Relative selectivity of some conformationally constrained tryptamine analogs at 5-HT1, 5-HT1A and 5-HT2 recognition sites. Life Sciences. 1987 Oct 19;41(16):1961-9. PMID 3657392
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