SLC12A7

SLC12A7
Identifiers
Aliases	SLC12A7, KCC4, solute carrier family 12 member 7
External IDs	OMIM: 604879; MGI: 1342283; HomoloGene: 21312; GeneCards: SLC12A7; OMA:SLC12A7 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	1,112,063 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	73,964,873 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; left ventricle; ; right lobe of liver; ; gallbladder; ; duodenum; ; right auricle; ; human kidney; ; body of stomach; ; spleen; ; granulocyte;
	Top expressed in
	vestibular membrane of cochlear duct; ; right ventricle; ; myocardium of ventricle; ; transitional epithelium of urinary bladder; ; cardiac muscle tissue of left ventricle; ; lumbar spinal ganglion; ; epithelium of stomach; ; left lobe of liver; ; interventricular septum; ; right kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transporter activity; cation:chloride symporter activity; symporter activity; protein kinase binding; potassium:chloride symporter activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane; plasma membrane; protein-containing complex;
Biological process	potassium ion transport; cell volume homeostasis; chloride transmembrane transport; chemical synaptic transmission; potassium ion transmembrane transport; transmembrane transport; ion transport; chloride ion homeostasis; potassium ion homeostasis; potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	10723
	20499
	ENSG00000276482; ENSG00000113504
	ENSMUSG00000017756
	Q9Y666
	Q9WVL3
	NM_006598
	NM_011390; NM_001360694
	NP_006589
	NP_035520; NP_001347623
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 12 member 7 is a protein that in humans is encoded by the SLC12A7 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c ENSG00000113504 GRCh38: Ensembl release 89: ENSG00000276482, ENSG00000113504 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000017756 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mount DB; Mercado A; Song L; Xu J; George AL Jr; Delpire E; Gamba G (Jul 1999). "Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family". J Biol Chem. 274 (23): 16355–62. doi:10.1074/jbc.274.23.16355. PMID 10347194.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: SLC12A7 solute carrier family 12 (potassium/chloride transporters), member 7".

SLC12A7

See also

References

Further reading