Zinc transporter ZIP10

SLC39A10
Identifiers
Aliases	SLC39A10, LZT-Hs2, solute carrier family 39 member 10
External IDs	OMIM: 608733; MGI: 1914515; HomoloGene: 34076; GeneCards: SLC39A10; OMA:SLC39A10 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	195,737,702 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	46,932,012 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; secondary oocyte; ; Brodmann area 46; ; superior frontal gyrus; ; Brodmann area 23; ; germinal epithelium; ; postcentral gyrus; ; right lobe of thyroid gland; ; dorsolateral prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	hand; ; hair follicle; ; otolith organ; ; utricle; ; secondary oocyte; ; primitive streak; ; primary motor cortex; ; cingulate gyrus; ; piriform cortex; ; primary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion transmembrane transporter activity; zinc ion transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	metal ion transport; negative regulation of B cell apoptotic process; positive regulation of protein tyrosine phosphatase activity; zinc ion transport; ion transport; positive regulation of B cell proliferation; transmembrane transport; cellular zinc ion homeostasis; positive regulation of B cell receptor signaling pathway; zinc ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	57181
	227059
	ENSG00000196950
	ENSMUSG00000025986
	Q9ULF5
	Q6P5F6
	NM_001127257; NM_020342
	NM_172653; NM_001356416; NM_001356417
	NP_001120729; NP_065075
	NP_766241; NP_001343345; NP_001343346
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc transporter ZIP10, also known as solute carrier family 39 member 10, is a protein that in humans is encoded by the SLC39A10 gene.^[5] ZIP10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters, and have 14 members in the human genome: ZIP1, ZIP2, ZIP3, ZIP4, ZIP5, ZIP6, ZIP7, ZIP8, ZIP9, ZIP10, ZIP11, ZIP12, ZIP13 and ZIP14.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196950 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025986 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Taylor KM, Morgan HE, Smart K, Zahari NM, Pumford S, Ellis IO, Robertson JF, Nicholson RI (Jul–Aug 2007). "The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer". Mol Med. 13 (7–8): 396–406. doi:10.2119/2007-00040.Taylor. PMC 1936980. PMID 17673939.
^ Eide DJ (February 2004). "The SLC39 family of metal ion transporters". Pflügers Arch. 447 (5): 796–800. doi:10.1007/s00424-003-1074-3. PMID 12748861. S2CID 11765308.

References

Further reading