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'''Furanylnorfentanyl''' is a potent short-acting synthetic [[opioid]] [[analgesic]] [[medication|drug]] precursor. It is an [[structural analog|analog]] of [[fentanyl]].<ref>{{cite journal |last1=Goggin |first1=Melissa M. |title=Identification of unique metabolites of the designer opioid furanyl fentanyl. |journal=Journal of Analytical Toxicology |date=2017 |volume=41 |issue=5 |page=367-375}}</ref><ref>{{cite journal |last1=Palmquist |first1=Kaitlyn B. |title=Quantification of furanylfentanyl and its metabolites in human and rat plasma using LC–MS-MS |journal=Journal of analytical toxicology |date=2020 |volume=44 |issue=6 |page=589-595}}</ref><ref>{{cite journal |last1=Larabi |first1=Islam Amine |title=Hair testing for 3-fluorofentanyl, furanylfentanyl, methoxyacetylfentanyl, carfentanil, acetylfentanyl and fentanyl by LC–MS/MS after unintentional overdose. |journal=Forensic Toxicology |date=2020 |volume=38 |issue=1 |page=277-286}}</ref><ref>{{cite journal |last1=Daniulaityte |first1=Raminta |title=Street fentanyl use: Experiences, preferences, and concordance between self-reports and urine toxicology. |journal=International Journal of Drug Policy |date=2019 |volume=71 |page=3-9}}</ref><ref>{{cite journal |last1=Shoemaker |first1=Alyssa K. |title=Cholinesterase Based System for Fentanyl Detection |journal=State University of New York at Albany |date=2020}}</ref>
'''Furanylnorfentanyl''' is a potent short-acting synthetic [[opioid]] [[analgesic]] [[medication|drug]] precursor. It is an [[structural analog|analog]] of [[fentanyl]].<ref>{{cite journal |last1=Goggin |first1=Melissa M. |title=Identification of unique metabolites of the designer opioid furanyl fentanyl. |journal=Journal of Analytical Toxicology |date=2017 |volume=41 |issue=5 |pages=367–375 |doi=10.1093/jat/bkx022 |pmid=28369517 }}</ref><ref>{{cite journal |last1=Palmquist |first1=Kaitlyn B. |title=Quantification of furanylfentanyl and its metabolites in human and rat plasma using LC–MS-MS |journal=Journal of Analytical Toxicology |date=2020 |volume=44 |issue=6 |pages=589–595 |doi=10.1093/jat/bkaa013 |pmid=32064536 }}</ref><ref>{{cite journal |last1=Larabi |first1=Islam Amine |title=Hair testing for 3-fluorofentanyl, furanylfentanyl, methoxyacetylfentanyl, carfentanil, acetylfentanyl and fentanyl by LC–MS/MS after unintentional overdose. |journal=Forensic Toxicology |date=2020 |volume=38 |issue=1 |page=277-286|doi=10.1007/s11419-019-00502-0 |s2cid=207916035 }}</ref><ref>{{cite journal |last1=Daniulaityte |first1=Raminta |title=Street fentanyl use: Experiences, preferences, and concordance between self-reports and urine toxicology. |journal=International Journal of Drug Policy |date=2019 |volume=71 |page=3-9|doi=10.1016/j.drugpo.2019.05.020 |pmid=31146200 |s2cid=171094309 }}</ref><ref>{{cite journal |last1=Shoemaker |first1=Alyssa K. |title=Cholinesterase Based System for Fentanyl Detection |journal=State University of New York at Albany |date=2020}}</ref>


==See also==
==See also==

Revision as of 09:32, 23 August 2022

Furanyl norfentanyl
Identifiers
  • N-phenyl-N-4-piperidinyl-2-furancarboxamide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC16H18F0N2O2
Molar mass270.332 g·mol−1
3D model (JSmol)
  • O=C(C1=CC=CO1)N(C2CCNCC2)C3=CC=CC=C3
  • InChI=1S/C16H18N2O2.ClH/c19-16(15-7-4-12-20-15)18(13-5-2-1-3-6-13)14-8-10-17-11-9-14;/h1-7,12,14,17H,8-11H2;1H
  • Key:CTLGGGXGCVGIOQ-UHFFFAOYSA-N

Furanylnorfentanyl is a potent short-acting synthetic opioid analgesic drug precursor. It is an analog of fentanyl.[1][2][3][4][5]

See also

References

  1. ^ Goggin, Melissa M. (2017). "Identification of unique metabolites of the designer opioid furanyl fentanyl". Journal of Analytical Toxicology. 41 (5): 367–375. doi:10.1093/jat/bkx022. PMID 28369517.
  2. ^ Palmquist, Kaitlyn B. (2020). "Quantification of furanylfentanyl and its metabolites in human and rat plasma using LC–MS-MS". Journal of Analytical Toxicology. 44 (6): 589–595. doi:10.1093/jat/bkaa013. PMID 32064536.
  3. ^ Larabi, Islam Amine (2020). "Hair testing for 3-fluorofentanyl, furanylfentanyl, methoxyacetylfentanyl, carfentanil, acetylfentanyl and fentanyl by LC–MS/MS after unintentional overdose". Forensic Toxicology. 38 (1): 277-286. doi:10.1007/s11419-019-00502-0. S2CID 207916035.
  4. ^ Daniulaityte, Raminta (2019). "Street fentanyl use: Experiences, preferences, and concordance between self-reports and urine toxicology". International Journal of Drug Policy. 71: 3-9. doi:10.1016/j.drugpo.2019.05.020. PMID 31146200. S2CID 171094309.
  5. ^ Shoemaker, Alyssa K. (2020). "Cholinesterase Based System for Fentanyl Detection". State University of New York at Albany.

Further reading

  • Higashikawa Y, Suzuki S (June 2008). "Studies on 1-(2-phenethyl)-4-(N-propionylanilino)piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues". Forensic Toxicology. 26 (1): 1–5. doi:10.1007/s11419-007-0039-1. S2CID 22092512.
  • Alburges ME, Hanson GR, Gibb JW, Sakashita CO, Rollins DE (1992). "Fentanyl receptor assay. II. Utilization of a radioreceptor assay for the analysis of fentanyl analogs in urine". J Anal Toxicol. 16 (1): 36–41. doi:10.1093/jat/16.1.36. PMID 1322477.
  • Woods J, Medzihradsky F, Smith C, Winger G, Gmerek D (1988). "Evaluation of new compounds for opioid activity: 1987 annual report". NIDA Res. Monogr. 81: 543–90. PMID 3136388.
  • Aceto M, Bowman E, Harris L, May E (1988). "Dependence studies of new compounds in the rhesus monkey, rat, and mouse, 1987". NIDA Res. Monogr. 81: 485–542. PMID 3136386.
  • Brine GA, Boldt KG, Huang PT, Sawyer DK, Carroll FI (2009). "Carbon-13 nuclear magnetic resonance spectra of fentanyl analogs". Journal of Heterocyclic Chemistry. 26 (3): 677–686. doi:10.1002/jhet.5570260329.
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