HOT-2
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| Names | |
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| IUPAC name
N-[2-(4-Ethylsulfanyl-2,5-dimethoxy-phenyl)-ethyl]-hydroxylamine
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| Other names
2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanaminol
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| Identifiers | |
3D model (JSmol)
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| ChEMBL | |
| ChemSpider | |
CompTox Dashboard (EPA)
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| Properties | |
| C12H19NO3S | |
| Molar mass | 257.347 g/mol |
| Melting point | 122 °C (252 °F; 395 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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HOT-2, or 2,5-dimethoxy-4-(β-ethylthio)-N-hydroxyphenethylamine is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book PiHKAL (Phenethylamines i Have Known And Loved).
Chemistry
HOT-2's full chemical name is 2-[4-(2-ethylthio)-2,5-dimethoxyphenyl–N–hydroxyethanamine. It has structural properties similar to 2C-T-2 and to other drugs in the HOT- series, with the most closely related compounds being HOT-7 and HOT-17.
General information
The dosage range of HOT-2 is typically 10-18 mg and its duration is approximately 6–10 hours according to Shulgin. HOT-2 produces visuals and moving, flowing lights. It also causes euphoria and increases blood pressure.