Jump to content

Ramosetron

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by CheMoBot (talk | contribs) at 14:09, 3 October 2016 (Updating {{infobox_drug}} (changes to verified and watched fields - updated 'KEGG_Ref') per Chem/infobox_drug validation (report errors or bugs)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Ramosetron
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		By mouth (ODT), IV
ATC code
  • None
Pharmacokinetic data
Elimination half-life5.8 hours
Identifiers
  • (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H17N3O
Molar mass279.33 g/mol g·mol−1
3D model (JSmol)
  • CN1C=C(C2=CC=CC=C21)C(=O)[C@@H]3CCC4=C(C3)NC=N4
  • InChI=1S/C17H17N3O/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14/h2-5,9-11H,6-8H2,1H3,(H,18,19)/t11-/m1/s1 ☒N
  • Key:NTHPAPBPFQJABD-LLVKDONJSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ramosetron (INN) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.[1] Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in males".[2] In India it is marketed under the brand name of IBset.

It is only licensed for use in Japan and selected Southeast Asian countries. In Japan it is sold under the trade name Iribo.[3] Elsewhere it is commonly sold under the trade name Nasea and in India as Nozia (150 μg/mL injection & 100 μg oral tablet).[4]

References

  1. ^ Fujii Y, Saitoh Y, Tanaka H, Toyooka H (February 2000). "Ramosetron for preventing postoperative nausea and vomiting in women undergoing gynecological surgery". Anesth. Analg. 90 (2): 472–5. doi:10.1097/00000539-200002000-00043. PMID 10648342.
  2. ^ http://www.astellas.com/en/corporate/news/detail/astellas-launches-irribow-for.html
  3. ^ Summary in Japanese. Retrieved on September 4, 2012.
  4. ^ Abridged prescribing information — Nasea (MIMS Philippines). Retrieved on June 13, 2008.
Stub icon

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Ramosetron&oldid=742404505"