Sodium-coupled neutral amino acid transporter 3

SLC38A3
Identifiers
Aliases	SLC38A3, G17, NAT1, SN1, SNAT3, solute carrier family 38 member 3
External IDs	OMIM: 604437; MGI: 1923507; HomoloGene: 4983; GeneCards: SLC38A3; OMA:SLC38A3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	50,221,486 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	107,546,729 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; muscle of thigh; ; body of pancreas; ; C1 segment; ; ganglionic eminence; ; right frontal lobe; ; ventricular zone; ; gastrocnemius muscle; ; caudate nucleus; ; amygdala;
	Top expressed in
	neural layer of retina; ; left lobe of liver; ; Epithelium of choroid plexus; ; muscle of thigh; ; soleus muscle; ; lumbar subsegment of spinal cord; ; right ventricle; ; superior frontal gyrus; ; primary visual cortex; ; ankle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	L-glutamine transmembrane transporter activity; L-histidine transmembrane transporter activity; L-asparagine transmembrane transporter activity; L-alanine transmembrane transporter activity; antiporter activity; symporter activity; amino acid transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; basolateral plasma membrane;
Biological process	L-alanine transport; sodium ion transport; histidine transport; female pregnancy; positive regulation of transcription from RNA polymerase II promoter in response to acidic pH; positive regulation of glutamine transport; brain development; asparagine transport; amino acid transport; cellular response to potassium ion starvation; glutamine transport; ion transport; amino acid transmembrane transport; transmembrane transport; L-histidine transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	10991
	76257
	ENSG00000188338
	ENSMUSG00000010064
	Q99624
	Q9DCP2
	NM_006841
	NM_001199217; NM_001199218; NM_023805
	NP_006832
	NP_001186146; NP_001186147; NP_076294
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium-coupled neutral amino acid transporter 3 is a protein that in humans is encoded by the SLC38A3 gene.^[5]^[6]^[7] Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188338 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000010064 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH (Feb 2000). "Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission". Cell. 99 (7): 769–80. doi:10.1016/S0092-8674(00)81674-8. PMID 10619430.
^ Fei YJ, Sugawara M, Nakanishi T, Huang W, Wang H, Prasad PD, Leibach FH, Ganapathy V (Sep 2000). "Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter". J Biol Chem. 275 (31): 23707–17. doi:10.1074/jbc.M002282200. PMID 10823827.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: SLC38A3 solute carrier family 38, member 3".

Sodium-coupled neutral amino acid transporter 3

See also

References

Further reading