Ammonia transporter: Difference between revisions
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Structurally related [[membrane transport protein]]s called Amt proteins (ammonia transporters, [[bacteria]] and [[plants]]), methylammonium/ammonium permeases (MEPs, in [[yeast]]) or [[RHAG|RhAG]], [[RHBG|RhBG]], and [[RHCG|RhCG]] [[Rh blood group system|Rh family]] members in [[mammal]]s. The ammonia transport protein AmtB from ''[[Escherichia coli]]'' was determined by [[x-ray crystallography]].<ref>{{Cite pmid|15361618}}</ref> The structure has a hydrophobic [[ammonia]] channel.<ref>{{Cite pmid|17119155}}</ref> The human RhCG ammonia transporter was found to have a similar ammonia-conducting channel structure.<ref>{{Cite pmid|20457942}}</ref> It was proposed that the [[erythrocyte]] Rh complex is a heterotrimer of RhAG, [[RhD]], and [[RHCE|RhCE]] subunits in which RhD and RhCE play roles in maintaining the ammonia-conducting RhAG subunit at the cell surface. |
Structurally related [[membrane transport protein]]s called Amt proteins (ammonia transporters, [[bacteria]] and [[plants]]), methylammonium/ammonium permeases (MEPs, in [[yeast]]) or [[RHAG|RhAG]], [[RHBG|RhBG]], and [[RHCG|RhCG]] [[Rh blood group system|Rh family]] members in [[mammal]]s. The ammonia transport protein AmtB from ''[[Escherichia coli]]'' was determined by [[x-ray crystallography]].<ref>{{Cite pmid|15361618}}</ref> The structure has a hydrophobic [[ammonia]] channel.<ref>{{Cite pmid|17119155}}</ref> The human RhCG ammonia transporter was found to have a similar ammonia-conducting channel structure.<ref>{{Cite pmid|20457942}}</ref> It was proposed that the [[erythrocyte]] Rh complex is a heterotrimer of RhAG, [[RhD]], and [[RHCE|RhCE]] subunits in which RhD and RhCE play roles in maintaining the ammonia-conducting RhAG subunit at the cell surface. Based on reconstitution experiments, purified RHCG subunits alone can function to transport ammonia.<ref>{{Cite pmid|20126667}}</ref> |
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==References== |
==References== |
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Revision as of 06:41, 11 September 2011
Structurally related membrane transport proteins called Amt proteins (ammonia transporters, bacteria and plants), methylammonium/ammonium permeases (MEPs, in yeast) or RhAG, RhBG, and RhCG Rh family members in mammals. The ammonia transport protein AmtB from Escherichia coli was determined by x-ray crystallography.[1] The structure has a hydrophobic ammonia channel.[2] The human RhCG ammonia transporter was found to have a similar ammonia-conducting channel structure.[3] It was proposed that the erythrocyte Rh complex is a heterotrimer of RhAG, RhD, and RhCE subunits in which RhD and RhCE play roles in maintaining the ammonia-conducting RhAG subunit at the cell surface. Based on reconstitution experiments, purified RHCG subunits alone can function to transport ammonia.[4]
References
- ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 15361618, please use {{cite journal}} with
|pmid=15361618instead. - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 17119155, please use {{cite journal}} with
|pmid=17119155instead. - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 20457942, please use {{cite journal}} with
|pmid=20457942instead. - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 20126667, please use {{cite journal}} with
|pmid=20126667instead.