SLC2A7

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Solute carrier family 2 (facilitated glucose transporter), member 7
Protein SLC2A7 PDB 1yg7.png
Rendering based on PDB 1yg7.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols SLC2A7 ; GLUT7
External IDs OMIM610371 MGI3650865 HomoloGene72470 GeneCards: SLC2A7 Gene
Orthologs
Species Human Mouse
Entrez 155184 435818
Ensembl ENSG00000197241 ENSMUSG00000062064
UniProt Q6PXP3 P0C6A1
RefSeq (mRNA) NM_207420 NM_001085529
RefSeq (protein) NP_997303 NP_001078998
Location (UCSC) Chr 1:
9.06 – 9.09 Mb
Chr 4:
150.15 – 150.17 Mb
PubMed search [1] [2]

Solute carrier family 2, facilitated glucose transporter member 7 also known as glucose transporter 7 (GLUT7) is a protein that in humans is encoded by the SLC2A7 gene.[1][2]

SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion.[2] This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues.[3]

See also[edit]

References[edit]

  1. ^ "Entrez Gene: solute carrier family 2 (facilitated glucose transporter)". 
  2. ^ a b Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI (July 2004). "Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine". Am. J. Physiol. Gastrointest. Liver Physiol. 287 (1): G236–42. doi:10.1152/ajpgi.00396.2003. PMID 15033637. 
  3. ^ Joost HG, Thorens B (2001). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)". Mol. Membr. Biol. 18 (4): 247–56. doi:10.1080/09687680110090456. PMID 11780753. 

Further reading[edit]

  • Manolescu A, Salas-Burgos AM, Fischbarg J, Cheeseman CI (2005). "Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7).". J. Biol. Chem. 280 (52): 42978–83. doi:10.1074/jbc.M508678200. PMID 16186102.