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Solute carrier family 25 (aspartate/glutamate carrier), member 12
Symbols SLC25A12 ; AGC1; ARALAR
External IDs OMIM603667 MGI1926080 HomoloGene48235 IUPHAR: 1054 GeneCards: SLC25A12 Gene
RNA expression pattern
PBB GE SLC25A12 203340 s at tn.png
PBB GE SLC25A12 203339 at tn.png
More reference expression data
Species Human Mouse
Entrez 8604 78830
Ensembl ENSG00000115840 ENSMUSG00000027010
UniProt O75746 Q8BH59
RefSeq (mRNA) NM_003705 NM_172436
RefSeq (protein) NP_003696 NP_766024
Location (UCSC) Chr 2:
172.64 – 172.86 Mb
Chr 2:
71.27 – 71.37 Mb
PubMed search [1] [2]

Calcium-binding mitochondrial carrier protein Aralar1 is a protein that in humans is encoded by the SLC25A12 gene.[1][2][3][4]

See also[edit]


  1. ^ del Arco A, Satrustegui J (Oct 1998). "Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain". J Biol Chem 273 (36): 23327–34. doi:10.1074/jbc.273.36.23327. PMID 9722566. 
  2. ^ Crackower MA, Sinasac DS, Lee JR, Herbrick JA, Tsui LC, Scherer SW (Apr 2000). "Assignment of the SLC25A12 gene coding for the human calcium-binding mitochondrial solute carrier protein aralar to human chromosome 2q24". Cytogenet Cell Genet 87 (3–4): 197–8. doi:10.1159/000015465. PMID 10702666. 
  3. ^ Palmieri L, Pardo B, Lasorsa FM, del Arco A, Kobayashi K, Iijima M, Runswick MJ, Walker JE, Saheki T, Satrustegui J, Palmieri F (Sep 2001). "Citrin and aralar1 are Ca2+-stimulated aspartate/glutamate transporters in mitochondria". EMBO J 20 (18): 5060–9. doi:10.1093/emboj/20.18.5060. PMC 125626. PMID 11566871. 
  4. ^ "Entrez Gene: SLC25A12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.