Sodium-dependent phosphate transport protein 2B

SLC34A2
Identifiers
Aliases	SLC34A2, NAPI-3B, NAPI-IIb, NPTIIb, solute carrier family 34 member 2, PULAM
External IDs	OMIM: 604217 MGI: 1342284 HomoloGene: 2297 GeneCards: SLC34A2
Gene location (Human)
Chr.	Chromosome 4 (human)
End	25,678,748 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	53,229,006 bp
RNA expression pattern
	Top expressed in
	lower lobe of lung; ; palpebral conjunctiva; ; upper lobe of lung; ; upper lobe of left lung; ; bronchial epithelial cell; ; right lung; ; right uterine tube; ; endometrium; ; minor salivary glands; ; right lobe of thyroid gland;
	Top expressed in
	left lung; ; left lung lobe; ; right lung; ; right lung lobe; ; ileum; ; jejunum; ; spermatocyte; ; spermatid; ; corneal stroma; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphate ion binding; sodium ion binding; sodium:phosphate symporter activity; symporter activity;
Cellular component	integral component of membrane; vesicle; membrane; plasma membrane; integral component of plasma membrane; brush border membrane; apical plasma membrane; brush border; cytoplasm;
Biological process	phosphate ion transport; sodium-dependent phosphate transport; sodium ion transport; cellular phosphate ion homeostasis; in utero embryonic development; response to estrogen; phosphate ion transmembrane transport; sodium ion transmembrane transport; ion transport; transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	10568
	20531
	ENSG00000157765
	ENSMUSG00000029188
	O95436
	Q9DBP0
	NM_006424; NM_001177998; NM_001177999
	NM_011402
	NP_001171469; NP_001171470; NP_006415
	NP_035532
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium-dependent phosphate transport protein 2B (NaPi2b) is a protein that in humans is encoded by the SLC34A2 gene.^[5]^[6]^[7] Template:PBB Summary

Clinical significance

Sodium-dependent phosphate transport protein 2b (NaPi2b) is a tumor-associated antigen.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000157765 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029188 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Feild JA, Zhang L, Brun KA, Brooks DP, Edwards RM (Jun 1999). "Cloning and functional characterization of a sodium-dependent phosphate transporter expressed in human lung and small intestine". Biochem Biophys Res Commun. 258 (3): 578–82. doi:10.1006/bbrc.1999.0666. PMID 10329428.
^ Xu H, Bai L, Collins JF, Ghishan FK (Feb 2000). "Molecular cloning, functional characterization, tissue distribution, and chromosomal localization of a human, small intestinal sodium-phosphate (Na+-Pi) transporter (SLC34A2)". Genomics. 62 (2): 281–4. doi:10.1006/geno.1999.6009. PMID 10610722.
^ "Entrez Gene: SLC34A2 solute carrier family 34 (sodium phosphate), member 2".
^ Yin BW, Kiyamova R, Chua R, Caballero OL, Gout I, Gryshkova V, Bhaskaran N, Souchelnytskyi S, Hellman U, Filonenko V, Jungbluth AA, Odunsi K, Lloyd KO, Old LJ, Ritter G. "Monoclonal antibody MX35 detects the membrane transporter NaPi2b (SLC34A2) in human carcinomas". Cancer Immun. 8: 3. PMC 2935786. PMID 18251464.

Sodium-dependent phosphate transport protein 2B

Clinical significance

See also

References

Further reading