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Glucose-6-phosphate exchanger SLC37A1 is a protein that in humans is encoded by the SLC37A1 gene.[5] SLC37A1 locates to the membrane of the endoplasmic reticulum (ER), and is a glucose 6-phosphate:inorganic phosphateantiporter, transporting glucose 6-phosphate from the cytoplasm into the lumen of the ER, while transporting phosphate in the opposite direction.[6]
Unlike the related SLC37A4 protein, SLC37A1 does not appear to be involved in blood glucosehomeostasis,[7] but does appear to regulate phosphate levels in the milk of cows, with flow-on effects on the volume of milk produced.[8]
Bartoloni L, Antonarakis SE (February 2004). "The human sugar-phosphate/phosphate exchanger family SLC37". Pflügers Archiv. 447 (5): 780–3. doi:10.1007/s00424-003-1105-0. PMID12811562.
