Zinc transporter ZIP4

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This is an old revision of this page, as edited by Havaborhan (talk | contribs) at 20:41, 13 September 2016 (Added a recent research about gene SLC39A4 which was published in 2015.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

solute carrier family 39 (zinc transporter), member 4
Identifiers
SymbolSLC39A4
Alt. symbolsAEZ
NCBI gene55630
HGNC17129
OMIM607059
RefSeqNM_130849
UniProtQ6P5W5
Other data
LocusChr. 8 q24.3
Search for
StructuresSwiss-model
DomainsInterPro

SLC39A4 is a transmembrane protein associated with acrodermatitis enteropathica.[1] Recently, researchers have hypothesized that acrodermatitis enteropathica may be caused by a mutation in the gene SLC39A4 coding for the hZip4 Zn transporter present in intestinal cells of the intestine.[2]

See also

References

  1. ^ Kambe T, Andrews GK (January 2009). "Novel proteolytic processing of the ectodomain of the zinc transporter ZIP4 (SLC39A4) during zinc deficiency is inhibited by acrodermatitis enteropathica mutations". Mol. Cell. Biol. 29 (1): 129–39. doi:10.1128/MCB.00963-08. PMC 2612479. PMID 18936158.
  2. ^ Beigi, Pooya Khan Mohammad; Maverakis, Emanual (2015-01-01). Acrodermatitis Enteropathica. Springer International Publishing. pp. 7–28. doi:10.1007/978-3-319-17819-6_2. ISBN 9783319178189.

External links


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