From Wikipedia, the free encyclopedia
Solute carrier family 41, member 3 is a protein that in humans is encoded by the SLC41A3 gene .[ 5]
Model organisms
Model organisms have been used in the study of SLC41A3 function. A conditional knockout mouse line, called Slc41a3tm1a(KOMP)Wtsi [ 10] [ 11] International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.[ 12] [ 13] [ 14]
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.[ 8] [ 15] mutant mice and one significant abnormality was observed: homozygous mutants displayed abnormal locomotor coordination.[ 8]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000114544 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030089 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: Solute carrier family 41, member 3" . Retrieved 2011-09-28 .^ "Salmonella infection data for Slc41a3" . Wellcome Trust Sanger Institute.^ "Citrobacter infection data for Slc41a3" . Wellcome Trust Sanger Institute.^ a b c Gerdin AK (2010). "The Sanger Mouse Genetics Programme: High throughput characterisation of knockout mice". Acta Ophthalmologica . 88 : 925–7. doi :10.1111/j.1755-3768.2010.4142.x . ^ Mouse Resources Portal , Wellcome Trust Sanger Institute.^ "International Knockout Mouse Consortium" .^ "Mouse Genome Informatics" .^ Skarnes, W. C.; Rosen, B.; West, A. P.; Koutsourakis, M.; Bushell, W.; Iyer, V.; Mujica, A. O.; Thomas, M.; Harrow, J.; Cox, T.; Jackson, D.; Severin, J.; Biggs, P.; Fu, J.; Nefedov, M.; De Jong, P. J.; Stewart, A. F.; Bradley, A. (2011). "A conditional knockout resource for the genome-wide study of mouse gene function" . Nature . 474 (7351): 337–342. doi :10.1038/nature10163 . PMC 3572410 PMID 21677750 . ^ Dolgin E (2011). "Mouse library set to be knockout". Nature . 474 (7351): 262–3. doi :10.1038/474262a . PMID 21677718 . ^ Collins FS; Rossant J; Wurst W (2007). "A Mouse for All Reasons". Cell . 128 (1): 9–13. doi :10.1016/j.cell.2006.12.018 . PMID 17218247 . ^ van der Weyden L; White JK; Adams DJ; Logan DW (2011). "The mouse genetics toolkit: revealing function and mechanism" . Genome Biol . 12 (6): 224. doi :10.1186/gb-2011-12-6-224 . PMC 3218837 PMID 21722353 . {{cite journal }}: CS1 maint: unflagged free DOI (link )
Further reading
Wabakken, T.; Rian, E.; Kveine, M.; Aasheim, H. C. (2003). "The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters". Biochemical and Biophysical Research Communications . 306 (3): 718–724. doi :10.1016/S0006-291X(03)01030-1 . PMID 12810078 .
By group
SLC1–10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21–30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31–40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41–48
(41): (42): (43): (44): (45): (46): (47): (48):
