XCR1

XCR1
Identifiers
Aliases	XCR1, CCGPR5, X-C motif chemokine receptor 1
External IDs	OMIM: 600552 MGI: 1346338 HomoloGene: 21095 GeneCards: XCR1
Gene location (Human) Chr. Chromosome 3 (human) Band 3p21.31 Start 46,016,990 bp End 46,085,825 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9 F4|9 74.71 cM Start 123,681,380 bp End 123,691,094 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lymph node appendix pancreatic ductal cell gallbladder skin of abdomen spleen rectum smooth muscle tissue thymus duodenum Top expressed in morula thymus spleen meninges duodenum jejunum blastocyst ventricular system choroid plexus retina More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity chemokine receptor activity signal transducer activity C-C chemokine receptor activity chemokine binding C-C chemokine binding Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane external side of plasma membrane Biological process positive regulation of cytosolic calcium ion concentration chemotaxis G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger inflammatory response signal transduction chemokine-mediated signaling pathway immune response calcium-mediated signaling cell chemotaxis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2829 23832 Ensembl ENSG00000173578 ENSMUSG00000060509 UniProt P46094 Q9R0M1 RefSeq (mRNA) NM_005283 NM_001024644 NM_001381860 NM_011798 RefSeq (protein) NP_001019815 NP_005274 NP_001368789 NP_035928 Location (UCSC) Chr 3: 46.02 – 46.09 Mb Chr 9: 123.68 – 123.69 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

The "C" sub-family of chemokine receptors contains only one member: XCR1, the receptor for XCL1 and XCL2 (or lymphotactin-1 and -2).

XCR1 is also known as GPR5.

External links

• "Chemokine Receptors: XCR1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

External links

• XCR1+receptor,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.