Seproxetine

Seproxetine
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Pharmacokinetic data
Elimination half-life	4-16 days
Identifiers
	IUPAC name (S)-3-Phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;
CAS Number	126924-38-7;
PubChem CID	4541;
IUPHAR/BPS	208;
DrugBank	DB06731;
ChemSpider	4382;
UNII	25CO3X0R31;
CompTox Dashboard (EPA)	DTXSID80866540 ;
Chemical and physical data
Formula	C16H16F3NO
Molar mass	295.30 g/mol g·mol−1

Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI). It is the most important active metabolite of the widely used antidepressant fluoxetine, but little is known about its pharmacological actions. Seproxetine was being investigated by Eli Lilly and Company as an antidepressant; however, a cardiac side effect was noted and development was discontinued.

References

^[1]

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

^ DrugBank, ed. (2013-09-16). "Seproxetine". DrugBank.

[1] DrugBank, ed. (2013-09-16). "Seproxetine". DrugBank.

[1]

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^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

v t e Eli Lilly and Company
Corporate directors	John C. Lechleiter Ralph Alvarez Sir Winfried Bischoff Michael L. Eskew Martin S. Feldstein J. Erik Fyrwald Alfred G. Gilman Karen N. Horn Ellen R. Marram Douglas R. Oberhelman Franklyn G. Prendergast Kathi P. Seifert
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