Brilacidin

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Brilacidin-.png
Systematic (IUPAC) name
N,N'-bis[3-{[5-(carbamimidoylamino)pentanoyl]amino}-2-[(3R)-pyrrolidin-3-yloxy]-5-(trifluoromethyl)phenyl]pyrimidine-4,6-dicarboxamide[1]
Clinical data
Trade names None as of July 2012[1]
Legal status ?
Identifiers
CAS number 1224095-98-0
ATC code None
PubChem CID 25023695
ChemSpider 28651526
ChEMBL CHEMBL2219413
Chemical data
Formula C40H50F6N14O6 
Mol. mass 936.9 g/mol

Brilacidin (formerly PMX-30063) is an antibiotic that works by disrupting bacterial cell membranes, mimicking defensins from innate immunity.[2][3]

Notes[edit]

  1. ^ a b STATEMENT ON A NONPROPRIETARY NAME ADOPTED BY THE USAN COUNCIL. American Medical Association. July 25, 2012. 
  2. ^ "brilacidin (formerly PMX-30063)". BioCentury BCIQ. BioCentury Publications. Retrieved 2013-09-19. 
  3. ^ Butler, Mark S; Cooper, Matthew A (18 May 2011). "Antibiotics in the clinical pipeline in 2011". The Journal of Antibiotics 64 (6): 413–425. doi:10.1038/ja.2011.44. 

References[edit]