Potassium canrenoate

Potassium canrenoate

Clinical data
Other names	SC-14266
AHFS/Drugs.com	International Drug Names
Routes of administration	Intravenous
ATC code	C03DA02 (WHO)
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Renal and fecal
Identifiers
IUPAC name potassium 3-[(8R,9S,10R,13S,14S,17R)- 17-hydroxy-10,13-dimethyl-3-oxo-2,8,9, 11,12,14,15,16-octahydro-1H-cyclopenta[a] phenanthren-17-yl]propanoate
CAS Number	2181-04-6 N
PubChem CID	23671691
DrugBank	DB09015 N
ChemSpider	570975 Y
UNII	M671F9NLEA
ChEMBL	ChEMBL1371200 N
CompTox Dashboard (EPA)	DTXSID2045602
ECHA InfoCard	100.016.868
Chemical and physical data
Formula	C22H29KO4
Molar mass	396.5616 g/mol g·mol−1
3D model (JSmol)	Interactive image
SMILES [K+].[O-]C(=O)CC[C@]3(O)CC[C@H]2[C@@H]4/C=C\C1=C\C(=O)CC[C@@]1([C@H]4CC[C@@]23C)C
InChI InChI=1S/C22H30O4.K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21,26)12-8-19(24)25;/h3-4,13,16-18,26H,5-12H2,1-2H3,(H,24,25);/q;+1/p-1/t16-,17+,18+,20+,21+,22-;/m1./s1 Y Key:JTZQCHFUGHIPDF-RYVBEKKQSA-M Y
NY (what is this?)  (verify)

Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium, the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body. Potassium canrenoate is not licensed in the UK, but may sometimes be prescribed off-licence to treat oedema. It is given intravenously.

See also

• Canrenone
• Prorenone
• Finerenone