Manidipine

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Manidipine
Manidipine.svg
Systematic (IUPAC) name
2-[4-(Diphenylmethyl)piperazin-1-yl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
  • Prescription only
Identifiers
CAS number 89226-50-6 120092-68-4
ATC code C08CA11
PubChem CID 4008
ChemSpider 3868
UNII 6O4754US88 YesY
Chemical data
Formula C35H38N4O6 
Molecular mass 610.69 g/mol

Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.[1][2][3][4][5]

References[edit]

  1. ^ Cheer, S.M.; McClellan, K. (2001), "Manidipine: A Review of its Use in Hypertension", Drugs 61 (12): 1777–99, doi:10.2165/00003495-200161120-00010, PMID 11693466, retrieved 2009-06-20 
  2. ^ McKeage, K.; Scott, L.J. (2004), "Manidipine: A Review of its Use in the Management of Hypertension", Drugs 64 (17): 1923–40, doi:10.2165/00003495-200464170-00011, PMID 15329044, retrieved 2009-06-20 
  3. ^ Roca-cusachs, A.; Triposkiadis, F. (2005), "Antihypertensive Effect of Manidipine", Drugs 65: 11–9, doi:10.2165/00003495-200565002-00003, PMID 16398058, retrieved 2009-06-20 
  4. ^ Otero, M.L. (2007), "Manidipine–delapril combination in the management of hypertension", Vascular Health and Risk Management 3 (3): 255–63, PMC 2293964, PMID 17703633 
  5. ^ Mizuno, Kenji; Hiroshi Haga, Michihiko Takahashi, Soitsu Fukuchi (August 1992), "Evaluation of manidipine hydrochloride, a new calcium antagonist, in the treatment of hypertensive patients with renal disorders", Current Therapeutic Research 52 (2): 248–253, doi:10.1016/S0011-393X(05)80475-8, retrieved 2009-06-20