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Enpiprazole

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Enpiprazole
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 1-(2-Chlorophenyl)-4-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]piperazine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H21ClN4
Molar mass304.82 g·mol−1
3D model (JSmol)
  • Clc3ccccc3N2CCN(CCc1cn(nc1)C)CC2

Enpiprazole (INN, BAN) is an anxiolytic drug of the phenylpiperazine group that was never marketed.[1][2] It produces anxiolytic-like effects in animals, though these effects appear to be biphasic and may reverse at high doses.[3] It is known to produce ortho-chlorophenylpiperazine (oCPP) as a metabolite.[4]

See also

References

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 488–. ISBN 978-1-4757-2085-3.
  2. ^ Bernan, British Pharmacopoeia Commission (2002). British Approved Names 2002. United Kingdom: The Stationery Office. p. 359. ISBN 0-11-322558-X.
  3. ^ Murasaki M, Hara T, Oguchi T, Inami M, Ikeda Y (September 1976). "Action of enpiprazole on emotional behavior induced by hypothalamic stimulation in rats and cats". Psychopharmacology. 49 (3): 271–4. doi:10.1007/BF00426829. PMID 12526. S2CID 10302402.
  4. ^ B.L. Goodwin (10 November 2004). Handbook of Biotransformations of Aromatic Compounds. CRC Press. pp. 3–. ISBN 978-0-203-64196-5.


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