Jump to content

Iodocyanopindolol

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Vanished user 0x8cSXE0x6 (talk | contribs) at 11:17, 1 October 2017. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Iodocyanopindolol
Skeletal formula of iodocyanopindolol
Space-filling model of the iodocyanopindolol molecule
Clinical data
ATC code
  • none
Identifiers
  • (RS)-4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3-iodo-1H-indole-2-carbonitrile
CAS Number
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H20IN3O2
Molar mass413.25 g/mol g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • IC1=C(C#N)NC2=CC=CC(OCC(CNC(C)(C)C)O)=C21
 ☒NcheckY (what is this?)  (verify)

Iodocyanopindolol (INN) is a drug related to pindolol which acts as both a β1 adrenoreceptor antagonist and a 5-HT1A receptor antagonist. Its 125I radiolabelled derivative has been widely used in mapping the distribution of beta adrenoreceptors in the body.[1]

References

  1. ^ Brodde OE, Karad K, Zerkowski HR, Rohm N, Reidemeister JC (1983). "Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding". Circulation Research. 53 (6): 752–758. doi:10.1161/01.res.53.6.752. PMID 6139182.



Stub icon

This antihypertensive-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Iodocyanopindolol&oldid=803247880"