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Revision as of 09:08, 31 July 2009

Quipazine
Clinical data
ATC code
  • none
Identifiers
  • 2-piperazin-1-ylquinoline
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.164.885 Edit this at Wikidata
Chemical and physical data
FormulaC13H15N3
Molar mass213.278 g/mol g·mol−1
3D model (JSmol)
  • C1CN(CCN1)C2=NC3=CC=CC=C3C=C2

Quipazine is a piperazine psychoactive drug and research chemical used in scientific studies. It is a moderately selective serotonin receptor agonist, binding to a range of different serotonin receptors, but particularly to the 5HT2A[1] and 5HT3 receptors.[2]

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References

  1. ^ Smith RL, Barrett RJ, Sanders-Bush E. Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor. Journal of Pharmacology and Experimental Therapeutics. 1995 Nov;275(2):1050-7. PMID 7473132
  2. ^ Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, Hamon M, Bruni G, Romeo MR, Menziani MC, De Benedetti PG, Langer T. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives. Journal of Medicinal Chemistry. 1998 Feb 26;41(5):728-41. PMID 9513601
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