Eclanamine

Eclanamine
Clinical data
ATC code	None;
Identifiers
	IUPAC name N-(3,4-dichlorophenyl)-N-[(1R,2R)-2-(dimethylamino)cyclopentyl]propanamide;
CAS Number	71027-14-0 ; 67450-45-7 (maleate);
PubChem CID	130380;
ChemSpider	115358;
UNII	5Y67H9W4KQ;
Chemical and physical data
Formula	C16H22Cl2N2O
Molar mass	329.26 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc2ccc(N(C(=O)CC)[C@@H]1CCC[C@H]1N(C)C)cc2Cl;
	InChI InChI=1S/C16H22Cl2N2O/c1-4-16(21)20(11-8-9-12(17)13(18)10-11)15-7-5-6-14(15)19(2)3/h8-10,14-15H,4-7H2,1-3H3/t14-,15-/m1/s1; Key:YCRFSKUCDBJWLX-HUUCEWRRSA-N;

Eclanamine (U-48,753) is a drug which was patented as an antidepressant, but was never marketed.^[1] It acts by inhibiting the reuptake of serotonin and norepinephrine.^[2] Eclanamine was discovered by accident as a derivative of the κ-opioid receptor agonist U-50,488.^[2]

References

^ David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9.
^ ^a ^b Progress in Medicinal Chemistry : Volume 29. Elsevier Science Pub Co. 1992. ISBN 0-444-89472-1.