AQP7

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Aquaporin 7
Identifiers
Symbols AQP7 ; AQP7L; AQP9; AQPap; GLYCQTL
External IDs OMIM602974 MGI1314647 HomoloGene48000 IUPHAR: AQP7 GeneCards: AQP7 Gene
RNA expression pattern
PBB GE AQP7 206955 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 364 11832
Ensembl ENSG00000165269 ENSMUSG00000028427
UniProt O14520 O54794
RefSeq (mRNA) NM_001170 NM_007473
RefSeq (protein) NP_001161 NP_031499
Location (UCSC) Chr 9:
33.38 – 33.4 Mb
Chr 4:
41.03 – 41.05 Mb
PubMed search [1] [2]

Aquaporin-7 is a protein that in humans is encoded by the AQP7 gene.[1][2]

Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function.[2]

See also[edit]

References[edit]

  1. ^ Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, Suzuki F, Marumo F, Sasaki S (Sep 1997). "Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea". J Biol Chem 272 (33): 20782–6. doi:10.1074/jbc.272.33.20782. PMID 9252401. 
  2. ^ a b "Entrez Gene: AQP7 aquaporin 7". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.