GJA10

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Gap junction protein, alpha 10, 62kDa
Identifiers
Symbols GJA10 ; CX62; RP11-63K6.6
External IDs OMIM611924 MGI1339969 HomoloGene7733 IUPHAR: Cx62 GeneCards: GJA10 Gene
Orthologs
Species Human Mouse
Entrez 84694 14610
Ensembl ENSG00000135355 ENSMUSG00000051056
UniProt Q969M2 Q9WUS4
RefSeq (mRNA) NM_032602 NM_010289
RefSeq (protein) NP_115991 NP_034419
Location (UCSC) Chr 6:
90.6 – 90.61 Mb
Chr 4:
32.6 – 32.6 Mb
PubMed search [1] [2]

Gap junction alpha-10 protein, also known as connexin-62 (Cx62), is a protein that in humans is encoded by the GJA10 gene.[1]

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[1][2]

References[edit]

  1. ^ a b "Entrez Gene: gap junction protein". 
  2. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.