GJD3

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Gap junction protein, delta 3, 31.9kDa
Identifiers
Symbols GJD3 ; CX31.9; Cx30.2; GJA11; GJC1
External IDs OMIM607425 MGI2384150 HomoloGene17530 IUPHAR: Cx31.9 GeneCards: GJD3 Gene
Orthologs
Species Human Mouse
Entrez 125111 353155
Ensembl ENSG00000183153 ENSMUSG00000047197
UniProt Q8N144 Q91YD1
RefSeq (mRNA) NM_152219 NM_178596
RefSeq (protein) NP_689343 NP_848711
Location (UCSC) Chr 17:
38.52 – 38.52 Mb
Chr 11:
98.98 – 98.98 Mb
PubMed search [1] [2]

Gap junction delta-2 (GJD2), also known as connexin-36 (Cx36) or gap junction alpha-9 (GJA9), is a protein that in humans is encoded by the GJD2 gene.[1]

Function[edit]

This gene is a member of the large family of connexins that are required for the formation of gap junctions. Six connexin monomers form a hemichannel, or connexon, on the cell surface. This connexon can interact with a connexon from a neighboring cell, thus forming a channel linking the cytoplasm of the 2 cells.[1]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.