KCNK10

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Potassium channel, subfamily K, member 10
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols KCNK10 ; K2p10.1; TREK-2; TREK2
External IDs OMIM605873 MGI1919508 HomoloGene11321 IUPHAR: K2P10.1 GeneCards: KCNK10 Gene
Orthologs
Species Human Mouse
Entrez 54207 72258
Ensembl ENSG00000100433 ENSMUSG00000033854
UniProt P57789 E9Q8H0
RefSeq (mRNA) NM_021161 NM_029911
RefSeq (protein) NP_066984 NP_084187
Location (UCSC) Chr 14:
88.65 – 88.79 Mb
Chr 12:
98.43 – 98.58 Mb
PubMed search [1] [2]

Potassium channel, subfamily K, member 10, also known as KCNK10 is a human gene. The protein encoded by this gene, K2P10.1, is a potassium channel containing two pore-forming P domains.[1][2]

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References[edit]

  1. ^ Lesage F, Terrenoire C, Romey G, Lazdunski M (September 2000). "Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors". J. Biol. Chem. 275 (37): 28398–405. doi:10.1074/jbc.M002822200. PMID 10880510. 
  2. ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (December 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol. Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. 

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