AQP9

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Aquaporin 9
Identifiers
Symbols AQP9 ; AQP-9; HsT17287; SSC1
External IDs OMIM602914 MGI1891066 HomoloGene41405 IUPHAR: AQP9 GeneCards: AQP9 Gene
Orthologs
Species Human Mouse
Entrez 366 64008
Ensembl ENSG00000103569 ENSMUSG00000032204
UniProt O43315 Q9JJJ3
RefSeq (mRNA) NM_020980 NM_001271843
RefSeq (protein) NP_066190 NP_001258772
Location (UCSC) Chr 15:
58.43 – 58.48 Mb
Chr 9:
71.11 – 71.17 Mb
PubMed search [1] [2]

Aquaporin-9 is a protein that in humans is encoded by the AQP9 gene.[1]

The aquaporins/major intrinsic protein are a family of water-selective membrane channels. Aquaporin 9 has greater sequence similarity with AQP3 and AQP7 and they may be a subfamily. Aquaporin 9 allows passage of a wide variety of noncharged solutes. AQP9 stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. Aquaporin 9 may also have some role in specialized leukocyte functions such as immunological response and bactericidal activity.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.