KCNK13
From Wikipedia, the free encyclopedia
| Potassium channel, subfamily K, member 13 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | KCNK13; K2p13.1; THIK-1; THIK1 | ||||||||||||
| External IDs | OMIM: 607367 MGI: 2384976 HomoloGene: 69351 IUPHAR: K2P13.1 GeneCards: KCNK13 Gene | ||||||||||||
|
|||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 56659 | 217826 | |||||||||||
| Ensembl | ENSG00000152315 | ENSMUSG00000045404 | |||||||||||
| UniProt | Q9HB14 | Q8R1P5 | |||||||||||
| RefSeq (mRNA) | NM_022054 | NM_146037 | |||||||||||
| RefSeq (protein) | NP_071337 | NP_666149 | |||||||||||
| Location (UCSC) | Chr 14: 90.53 – 90.65 Mb |
Chr 12: 101.2 – 101.3 Mb |
|||||||||||
| PubMed search | [1] | [2] | |||||||||||
Potassium channel, subfamily K, member 13, also known as KCNK13 is a human gene. The protein encoded by this gene, K2P13.1 is a potassium channel containing two pore-forming P domains.[1][2]
Contents |
[edit] See also
[edit] References
- ^ Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C (March 2001). "THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels". J. Biol. Chem. 276 (10): 7302–11. doi:10.1074/jbc.M008985200. PMID 11060316.
- ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (December 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol. Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106.
[edit] Further reading
- Strausberg RL, Feingold EA, Grouse LH et al (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Fearon IM, Campanucci VA, Brown ST et al (2006). "Acute hypoxic regulation of recombinant THIK-1 stably expressed in HEK293 cells". Adv. Exp. Med. Biol.. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 580: 203–8; discussion 351–9. doi:10.1007/0-387-31311-7_31. ISBN 978-0-387-31310-8. PMID 16683720.
- Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (2001). "Potassium leak channels and the KCNK family of two-P-domain subunits". Nat. Rev. Neurosci. 2 (3): 175–84. doi:10.1038/35058574. PMID 11256078.
- Gerhard DS, Wagner L, Feingold EA et al (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Theilig F, Goranova I, Hirsch JR et al (2008). "Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney". Cell. Physiol. Biochem. 21 (1–3): 63–74. doi:10.1159/000113748. PMID 18209473.
- Gierten J, Ficker E, Bloehs R et al (2008). "Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein". Br. J. Pharmacol. 154 (8): 1680–90. doi:10.1038/bjp.2008.213. PMC 2518462. PMID 18516069. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2518462.
[edit] External links
 |
This membrane protein-related article is a stub. You can help Wikipedia by expanding it. |
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
