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Potassium inwardly-rectifying channel, subfamily J, member 16
Symbols KCNJ16 ; BIR9; KIR5.1
External IDs OMIM605722 MGI1314842 HomoloGene23112 IUPHAR: 440 GeneCards: KCNJ16 Gene
RNA expression pattern
PBB GE KCNJ16 219564 at tn.png
More reference expression data
Species Human Mouse
Entrez 3773 16517
Ensembl ENSG00000153822 ENSMUSG00000051497
UniProt Q9NPI9 Q9Z307
RefSeq (mRNA) NM_001270422 NM_001252207
RefSeq (protein) NP_001257351 NP_001239136
Location (UCSC) Chr 17:
68.05 – 68.13 Mb
Chr 11:
110.97 – 111.03 Mb
PubMed search [1] [2]

Potassium inwardly-rectifying channel, subfamily J, member 16 (KCNJ16) is a human gene encoding the Kir5.1 protein.[1]

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Kir5.1 is an integral membrane protein and inward-rectifier type potassium channel. Kir5.1, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.