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Lorpiprazole

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Lorpiprazole
Clinical data
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • (5aR,8aS)-3-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-5,5a,6,7,8,8a-hexahydrocyclopenta[3,4]pyrrolo[2,1-c][1,2,4]triazole
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H26F3N5
Molar mass405.46 g/mol g·mol−1
3D model (JSmol)
  • FC(F)(F)c1cc(ccc1)N5CCN(CCc4nnc2n4C[C@@H]3CCC[C@H]23)CC5

Lorpiprazole (INN) (brand name Normarex) is a marketed anxiolytic drug of the phenylpiperazine group.[1][2][3] It has been described as a serotonin antagonist and reuptake inhibitor (SARI) in the same group as trazodone, nefazodone, and etoperidone.[3]

See also

References

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 742–. ISBN 978-1-4757-2085-3.
  2. ^ Hans -Georg Scharnow; Negwer, Martin (2001). Organic-Chemical Drugs and Their Synonyms, 8th Edition (v. 1-6). Weinheim: Wiley-VCH. ISBN 3-527-30247-6.
  3. ^ a b Fagiolini, Andrea; Comandini, Alessandro; Dell’Osso, Mario Catena; Kasper, Siegfried (2012). "Rediscovering Trazodone for the Treatment of Major Depressive Disorder". CNS Drugs. 26 (12): 1033–1049. doi:10.1007/s40263-012-0010-5. ISSN 1172-7047. PMC 3693429. PMID 23192413.


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