KCNK13: Difference between revisions
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{{PBB|geneid=56659}} |
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{{protein |
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| name = potassium channel, subfamily K, member 13 |
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| caption = |
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| image = |
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| width = |
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| HGNCid = 6275 |
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| Symbol = KCNK13 |
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| AltSymbols = K2p13.1 |
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| EntrezGene = 56659 |
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| OMIM = 607367 |
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| RefSeq = NM_022054 |
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| UniProt = Q9HB14 |
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| PDB = |
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| ECnumber = |
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| Chromosome = 14 |
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| Arm = q |
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| Band = 32.11 |
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| LocusSupplementaryData = |
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}} |
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'''Potassium channel, subfamily K, member 13''', also known as '''KCNK13''' is a human [[gene]]. The [[protein]] encoded by this gene, K<sub>2P</sub>13.1 is a [[potassium channel]] containing two pore-forming P domains.<ref name="pmid11060316">{{cite journal | author = Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C | title = THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels | journal = J. Biol. Chem. | volume = 276 | issue = 10 | pages = 7302–11 | year = 2001 | month = March | pmid = 11060316 | doi = 10.1074/jbc.M008985200 | url = | issn = }}</ref><ref name="pmid16382106">{{cite journal | author = Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S | title = International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels | journal = Pharmacol. Rev. | volume = 57 | issue = 4 | pages = 527–40 | year = 2005 | month = December | pmid = 16382106 | doi = 10.1124/pr.57.4.12 | url = | issn = }}</ref> |
'''Potassium channel, subfamily K, member 13''', also known as '''KCNK13''' is a human [[gene]]. The [[protein]] encoded by this gene, K<sub>2P</sub>13.1 is a [[potassium channel]] containing two pore-forming P domains.<ref name="pmid11060316">{{cite journal | author = Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C | title = THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels | journal = J. Biol. Chem. | volume = 276 | issue = 10 | pages = 7302–11 | year = 2001 | month = March | pmid = 11060316 | doi = 10.1074/jbc.M008985200 | url = | issn = }}</ref><ref name="pmid16382106">{{cite journal | author = Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S | title = International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels | journal = Pharmacol. Rev. | volume = 57 | issue = 4 | pages = 527–40 | year = 2005 | month = December | pmid = 16382106 | doi = 10.1124/pr.57.4.12 | url = | issn = }}</ref> |
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==References== |
==References== |
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{{Reflist}} |
{{Reflist}} |
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==Further reading== |
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{{refbegin | 2}} |
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*{{cite journal |author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }} |
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*{{cite journal |author=Fearon IM, Campanucci VA, Brown ST, ''et al.'' |title=Acute hypoxic regulation of recombinant THIK-1 stably expressed in HEK293 cells. |journal=Adv. Exp. Med. Biol. |volume=580 |issue= |pages= 203-8; discussion 351-9 |year= 2006 |pmid= 16683720 |doi= 10.1007/0-387-31311-7_31 }} |
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*{{cite journal |author=Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N |title=Potassium leak channels and the KCNK family of two-P-domain subunits. |journal=Nat. Rev. Neurosci. |volume=2 |issue= 3 |pages= 175-84 |year= 2001 |pmid= 11256078 |doi= }} |
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*{{cite journal |author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }} |
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*{{cite journal |author=Theilig F, Goranova I, Hirsch JR, ''et al.'' |title=Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney. |journal=Cell. Physiol. Biochem. |volume=21 |issue= 1-3 |pages= 63-74 |year= 2008 |pmid= 18209473 |doi= 10.1159/000113748 }} |
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*{{cite journal |author=Gierten J, Ficker E, Bloehs R, ''et al.'' |title=Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein. |journal=Br. J. Pharmacol. |volume=154 |issue= 8 |pages= 1680-90 |year= 2008 |pmid= 18516069 |doi= 10.1038/bjp.2008.213 }} |
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{{refend}} |
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== External links == |
== External links == |
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*{{cite web | url = http://www.iuphar-db.org/IC/ObjectDisplayForward?objectId=140&familyId=18 | title = Two-P Potassium Channels: K<sub>2P</sub>13.1 | accessdate = | author = | authorlink = | coauthors = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }} |
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* {{MeshName|KCNK13+protein,+human}} |
* {{MeshName|KCNK13+protein,+human}} |
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{{membrane-protein-stub}} |
{{membrane-protein-stub}} |
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{{Ion channels}} |
{{Ion channels|g3}} |
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[[Category:Ion channels]] |
[[Category:Ion channels]] |
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Revision as of 16:01, 17 September 2009
Potassium channel, subfamily K, member 13, also known as KCNK13 is a human gene. The protein encoded by this gene, K2P13.1 is a potassium channel containing two pore-forming P domains.[1][2]
See also
References
- ^ Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C (2001). "THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels". J. Biol. Chem. 276 (10): 7302–11. doi:10.1074/jbc.M008985200. PMID 11060316.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) - ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol. Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link)
Further reading
- Strausberg RL, Feingold EA, Grouse LH; et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Fearon IM, Campanucci VA, Brown ST; et al. (2006). "Acute hypoxic regulation of recombinant THIK-1 stably expressed in HEK293 cells". Adv. Exp. Med. Biol. 580: 203–8, discussion 351-9. doi:10.1007/0-387-31311-7_31. PMID 16683720.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (2001). "Potassium leak channels and the KCNK family of two-P-domain subunits". Nat. Rev. Neurosci. 2 (3): 175–84. PMID 11256078.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Theilig F, Goranova I, Hirsch JR; et al. (2008). "Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney". Cell. Physiol. Biochem. 21 (1–3): 63–74. doi:10.1159/000113748. PMID 18209473.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - Gierten J, Ficker E, Bloehs R; et al. (2008). "Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein". Br. J. Pharmacol. 154 (8): 1680–90. doi:10.1038/bjp.2008.213. PMID 18516069.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link)
External links
- KCNK13+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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