Keratin 3
Keratin 3 also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene.[1][2] Keratin 3 is a type II cytokeratin. It is specifically found in the corneal epithelium together with keratin 12.
Mutations in the KRT3 encoding this protein have been associated with Meesmanns Corneal Dystrophy.[3]
References
- ^ Raimondi E, Moralli D, De Carli L, Ceratto N, Balzaretti M, Leube R, Collin C, Romano V (1994). "Assignment of the human cytokeratin 3 gene (KRT3) to 12q12-->q13 by FISH". Cytogenet. Cell Genet. 66 (3): 162–3. doi:10.1159/000133690. PMID 7510223.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Irvine AD, Corden LD, Swensson O, Swensson B, Moore JE, Frazer DG, Smith FJ, Knowlton RG, Christophers E, Rochels R, Uitto J, McLean WH (June 1997). "Mutations in cornea-specific keratin K3 or K12 genes cause Meesmann's corneal dystrophy". Nat. Genet. 16 (2): 184–7. doi:10.1038/ng0697-184. PMID 9171831.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
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