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Keratin 33B, type I
Symbols KRT33B ; HA3II; Ha-3II; K33B; KRTHA3A; KRTHA3B; hHa3-II
External IDs OMIM602762 MGI1309991 HomoloGene136754 GeneCards: KRT33B Gene
RNA expression pattern
PBB GE KRT33B 207787 at tn.png
PBB GE KRT31 208483 x at tn.png
More reference expression data
Species Human Mouse
Entrez 3884 16671
Ensembl ENSG00000131738 ENSMUSG00000057723
UniProt Q14525 Q61897
RefSeq (mRNA) NM_002279 NM_013570
RefSeq (protein) NP_002270 NP_038598
Location (UCSC) Chr 17:
41.36 – 41.4 Mb
Chr 11:
100.02 – 100.03 Mb
PubMed search [1] [2]

Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.[1][2][3]

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[3]


  1. ^ Rogers MA, Schweizer J, Kreig T, Winter H (Nov 1995). "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep 20 (3): 155–61. doi:10.1007/BF00990548. PMID 7565656. 
  2. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889. 
  3. ^ a b "Entrez Gene: KRT33B keratin 33B". 

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