MYH13

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MYH13
Identifiers
AliasesMYH13, MyHC-IIL, MyHC-eo, myosin, heavy chain 13, skeletal muscle, myosin heavy chain 13
External IDsOMIM: 603487 MGI: 1339967 HomoloGene: 55780 GeneCards: MYH13
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for MYH13
Genomic location for MYH13
Band17p13.1Start10,300,865 bp[1]
End10,373,130 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003802

NM_001081250

RefSeq (protein)

NP_003793

n/a

Location (UCSC)Chr 17: 10.3 – 10.37 MbChr 11: 67.32 – 67.37 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myosin-13 also known as myosin, heavy chain 13 is a protein which in humans is encoded by the MYH13 gene.[5]

Function[edit]

MYH13 is a myosin whose expression is restricted primarily to the extrinsic eye muscles which are specialized for function in eye movement.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000006788 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060180 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Winters LM, Briggs MM, Schachat F (November 1998). "The human extraocular muscle myosin heavy chain gene (MYH13) maps to the cluster of fast and developmental myosin genes on chromosome 17". Genomics. 54 (1): 188–9. doi:10.1006/geno.1998.5558. PMID 9806854.
  6. ^ Weiss A, Schiaffino S, Leinwand LA (July 1999). "Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity". J. Mol. Biol. 290 (1): 61–75. doi:10.1006/jmbi.1999.2865. PMID 10388558.

Further reading[edit]