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Keratin 33A, type I
Symbols KRT33A ; HA3I; Ha-3I; K33A; KRTHA3A; Krt1-3; hHa3-I
External IDs OMIM602761 MGI1919138 HomoloGene135742 GeneCards: KRT33A Gene
RNA expression pattern
PBB GE KRT31 208483 x at tn.png
More reference expression data
Species Human Mouse
Entrez 3883 71888
Ensembl ENSG00000006059 ENSMUSG00000035592
UniProt O76009 Q8K0Y2
RefSeq (mRNA) NM_004138 NM_027983
RefSeq (protein) NP_004129 NP_082259
Location (UCSC) Chr 17:
41.35 – 41.35 Mb
Chr 11:
100.01 – 100.02 Mb
PubMed search [1] [2]

Keratin, type I cuticular Ha3-I is a protein that in humans is encoded by the KRT33A gene.[1][2][3]

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[3]


  1. ^ Rogers MA, Schweizer J, Kreig T, Winter H (Nov 1995). "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms". Mol Biol Rep 20 (3): 155–61. doi:10.1007/BF00990548. PMID 7565656. 
  2. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889. 
  3. ^ a b "Entrez Gene: KRT33A keratin 33A". 

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