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Cl-formate exchanger

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The Cl−-formate exchanger, otherwise known as Pendrin[1] encoded by the SLC26A4 gene,[2] is a transport protein present in the kidney,[3] where it functions in the renal chloride reabsorption. It is also present in vascular smooth muscle and cardiac muscle.[4]

References

  1. ^ Knauf, Felix; Yang, Chao-Ling; Thomson, R. Brent; Mentone, Sue Ann; Giebisch, Gerhard; Aronson, Peter S. (2001-07-31). "Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells". Proceedings of the National Academy of Sciences. 98 (16): 9425–9430. Bibcode:2001PNAS...98.9425K. doi:10.1073/pnas.141241098. ISSN 0027-8424. PMC 55437. PMID 11459928.
  2. ^ Da, Scott; Lp, Karniski (January 2000). "Human Pendrin Expressed in Xenopus Laevis Oocytes Mediates Chloride/Formate Exchange". American Journal of Physiology. Cell Physiology. 278 (1): C207-11. doi:10.1152/ajpcell.2000.278.1.C207. PMID 10644529.
  3. ^ Chloride/Formate Exchange with Formic Acid Recycling: A Mechanism of Active Chloride Transport across Epithelial Membranes Lawrence P. Karniski and Peter S. Aronson
  4. ^ Presence of chloride-formate exchange in vascular smooth muscle and cardiac cells M Soleimani and RL Howard. Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5116.
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