Protein 4.2

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EPB42
Identifiers
Aliases EPB42, PA, SPH5, erythrocyte membrane protein band 4.2
External IDs OMIM: 177070 MGI: 95402 HomoloGene: 93 GeneCards: EPB42
RNA expression pattern
PBB GE EPB42 210746 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000119
NM_001114134

NM_013513

RefSeq (protein)

NP_000110
NP_001107606

NP_038541.1
NP_038541

Location (UCSC) Chr 15: 43.11 – 43.22 Mb Chr 2: 121.02 – 121.04 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Erythrocyte membrane protein band 4.2 is a protein that in humans is encoded by the EPB42 gene.[3][4]

Protein 4.2 is a cytoskeleton protein found in red blood cells.

Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia.[4]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ White RA, Peters LL, Adkison LR, Korsgren C, Cohen CM, Lux SE (Jun 1993). "The murine pallid mutation is a platelet storage pool disease associated with the protein 4.2 (pallidin) gene". Nat Genet. 2 (1): 80–83. doi:10.1038/ng0992-80. PMID 1284644. 
  4. ^ a b "Entrez Gene: EPB42 erythrocyte membrane protein band 4.2". 

Further reading[edit]

External links[edit]