Methoxyketamine: Difference between revisions
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| CASNo1 = 6728-62-7 |
| CASNo1 = 6728-62-7 |
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| CASNo1_Comment =([[hydrochloride|HCl]]) |
| CASNo1_Comment =([[hydrochloride|HCl]]) |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = U4I8JIS24N |
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| UNII1_Ref = {{fdacite|correct|FDA}} |
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| UNII1 = 2OVB5UO35R |
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| UNII1_Comment = ([[hydrochloride|HCl]]) |
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| PubChem = 57483650 |
| PubChem = 57483650 |
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| ChemSpiderID = 27470964 |
| ChemSpiderID = 27470964 |
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Revision as of 16:43, 24 June 2020
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| Names | |
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| IUPAC name
2-(2-Methoxyphenyl)-2-(methylamino)cyclohexanone
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C14H19NO2 | |
| Molar mass | 233.311 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Methoxyketamine or 2-MeO-2-deschloroketamine is a designer drug of the arylcyclohexylamine class first reported in 1963.[1] It is an analog of ketamine in which the chlorine atom has been replaced with a methoxy group. Its synthesis by rearrangement of an amino ketone has been reported.[2] As an arylcyclohexylamine, methoxyketamine most likely functions as an NMDA receptor antagonist. It may produce sedative, hallucinogenic, and (at high doses) anesthetic effects.
References
- ^ BE 634208, Stevens, Calvin L., "Amino ketones", published 1963
- ^ Stevens, Calvin L.; Thuillier, Andre; Taylor, K. Grant; Daniher, Francis A.; Dickerson, James P.; Hanson, Harry T.; Nielsen, Norman A.; Tikotkar, N. A.; Weier, Richard M. (1966). "Amino Ketone Rearrangements. VII.1 Synthesis of 2-Methylamino-2-Substituted Phenylcyclohexanones". The Journal of Organic Chemistry. 31 (8): 2601. doi:10.1021/jo01346a034.
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